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Page 1
A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms.
Harter P, Sehouli J, Lorusso D, Reuss A, Vergote I, Marth C, Kim JW, Raspagliesi F, Lampe B, Aletti G, Meier W, Cibula D, Mustea A, Mahner S, Runnebaum IB, Schmalfeldt B, Burges A, Kimmig R, Scambia G, Greggi S, Hilpert F, Hasenburg A, Hillemanns P, Giorda G, von Leffern I, Schade-Brittinger C, Wagner U, du Bois A. Harter P, et al. Among authors: von leffern i. N Engl J Med. 2019 Feb 28;380(9):822-832. doi: 10.1056/NEJMoa1808424. N Engl J Med. 2019. PMID: 30811909 Free article. Clinical Trial.
High homogeneity of MMR deficiency in ovarian cancer.
Fraune C, Rosebrock J, Simon R, Hube-Magg C, Makrypidi-Fraune G, Kluth M, Büscheck F, Höflmayer D, Schmalfeldt B, Müller V, Wölber L, Witzel I, Paluchowski P, Wilke C, Heilenkötter U, von Leffern I, Clauditz TS, Wilczak W, Sauter G, Steurer S, Burandt E. Fraune C, et al. Among authors: von leffern i. Gynecol Oncol. 2020 Mar;156(3):669-675. doi: 10.1016/j.ygyno.2019.12.031. Epub 2020 Jan 8. Gynecol Oncol. 2020. PMID: 31924330
High mitochondrial content is associated with breast cancer aggressiveness.
Lebok P, Schütt K, Kluth M, Witzel I, Wölber L, Paluchowski P, Terracciano L, Wilke C, Heilenkötter U, Müller V, Schmalfeldt B, Simon R, Sauter G, Von Leffern I, Krech T, Krech RH, Jacobsen F, Burandt E. Lebok P, et al. Among authors: von leffern i. Mol Clin Oncol. 2021 Oct;15(4):203. doi: 10.3892/mco.2021.2365. Epub 2021 Aug 8. Mol Clin Oncol. 2021. PMID: 34462659 Free PMC article.
MUC5AC expression is linked to mucinous/endometroid subtype, absence of nodal metastasis and mismatch repair deficiency in ovarian cancer.
Rico SD, Schmalfeldt B, Müller V, Wölber L, Witzel I, Paluchowski P, von Leffern I, Heilenkötter U, Jacobsen F, Bernreuther C, Clauditz T, Simon R, Steurer S, Burandt E, Marx AH, Krech T. Rico SD, et al. Among authors: von leffern i. Pathol Res Pract. 2021 Aug;224:153533. doi: 10.1016/j.prp.2021.153533. Epub 2021 Jun 21. Pathol Res Pract. 2021. PMID: 34171599
A shift from membranous and stromal syndecan-1 (CD138) expression to cytoplasmic CD138 expression is associated with poor prognosis in breast cancer.
Kind S, Jaretzke A, Büscheck F, Möller K, Dum D, Höflmayer D, Hinsch A, Weidemann S, Fraune C, Möller-Koop C, Hube-Magg C, Simon R, Wilczak W, Lebok P, Witzel I, Müller V, Schmalfeldt B, Paluchowski P, Wilke C, Heilenkötter U, von Leffern I, Krech T, Krech RH, von der Assen A, Bawahab AA, Burandt E. Kind S, et al. Among authors: von leffern i. Mol Carcinog. 2019 Dec;58(12):2306-2315. doi: 10.1002/mc.23119. Epub 2019 Sep 23. Mol Carcinog. 2019. PMID: 31545001